If you are in search of that once-in-a-lifetime luxury vacation that takes you to the ultimate off-the-beaten-path destination, there are five places you might want to consider. In order to find that perfect location that offers exclusive luxury, a unique location, and a vacation you will be remembering in your dreams, you have to look beyond the normal and mundane and into the extraordinary.Petite Anse Beach, SeychellesWhen you think of an off-trail breathtaking place to visit, Seychelles should definitely come to mind. Located on the mesmerizing Petite Anse Beach in Baie Lazare, The Four Seasons Resort offers a tree-house villa perched on a granite hillside overlooking the ocean.This will be your own version of Eden as you spend your days lounging in the azure waters, bathing in the private pool, or getting a spa treatment before sitting down for a sunset dinner on the deserted beach.The one-bedroom villas with private balconies are surrounded by lush, green, jungles and offer spectacular views of the Petite Anse bay. Get the 5-star experience at Four Seasons in one of the most beautiful and remote locations on the planet.Image: SplashNgorongoro Conservation Area, TanzaniaLooking for a more adventurous stay in a remote location? Try a visit to Tanzania where the excitement of a safari meets the comforts of a luxury vacation. The Highlands camp, located at the Ngorongoro Conservation Area is home base with breathtaking views of the famous Mt. Kilimanjaro.If you enjoy the perfect climate and would like to get back to nature, this is the vacation for you. Enjoy first-class accommodations and fine cuisine while experiencing the thrill of the wildest African habitats. Your personal domed tent is equipped with everything you need to relax and rest as your gourmet meals are being prepared with organic, locally grown ingredients.Image: Trey Ratcliff (Own Work), CC BY-NC-SA 2.0, via FlickrSkylofts, Las VegasFor the ultimate luxury vacation that offers a unique view of the world around you, try the Skylofts at MGM Grand. This resort is internationally acclaimed and rated as a Forbes Five-Star and AAA Five-Diamond destination. It’s one of the exclusive Leading Hotels of the World and was revealed as a private sanctuary featuring sleek two-story units.You will be bathed in luxury with your private balcony overlooking the mountain view. With rooms ranging from 1,400 to 6,000 square feet, you will be sure to find the perfect match for your ideal vacation. Your private butler service will make sure all your needs are met. The on-site restaurant, casino, pool, and fitness center, make this a comprehensive stay without ever leaving your private sanctuary.While you’re enjoying your luxury stay in Vegas, you may want to branch out and experience some of the breathtaking destinations in Nevada. What better way to do that than in the comfort of an RV rental in Las Vegas. Have the freedom to explore nearby spots such as Lake Mead, Sedona, Laughlin (mini Vegas), or Zion National Park in Utah.Image: Wpcpey (Own Work), CC BY-SA 4.0, via WikimediaSky Lobby, Tokyo, JapanDefinitely considered a vacation less taken, Tokyo has become an increasingly popular destination for the ultimate in luxury accommodations. Japan prides itself on catering to those with high-end expectations for a unique first-class experience.While there are many places to choose from for a visit to Tokyo, The Prince Gallery Tokyo Kioicho is the bell of the ball. Close enough to the city to enjoy the feast and delights only this city offers, there are also plenty of places to experience the outdoors. If shopping is your delight, you will find no better spot to visit some of the finest shopping opportunities any city has to offer.When it comes to luxury, this 5-star hotel will blow you away as you step into the enormous Sky Lobby filled with abundant and natural light. Each room and suite is immaculately designed and feature unparalleled views of Tokyo. Complete with every possible accommodation, each room is equipped with Luxury Collection bath amenities and restorative retreat options. This hotel offers restaurants and bars with a distinctive cuisine and uncompromising service perfected over thousands of years from the welcoming culture of Japan.Image: Mag Master (Own Work), via FlickrAmarna Resort, AustraliaFor a truly off-the-beaten-path location with a 5-star resort rating, you have to consider the Amarna Resort. This oasis sits on a private, secluded beach. Just 2 1/1 hours from Sydney, this resort is the perfect marriage of luxury and memorable experience.These contemporary apartments all feature a private deck and panoramic ocean views. The pristine and guest-only beach boasts a heated outdoor pool and spa which allows you to relax in ultimate comfort as you watch the fire-injected sunsets, bathed in the cool sea breezes.Go dolphin watching, take a morning swim, venture out on a paddleboard or kayak. In-room massages are available to complete this ultimate vacation.You might want to consider visiting more of the continent down under before or after your stay at the Amarna Resort. If you are a fan of cruising, you might want to discover Australia’s last-minute cruises. Make your stay in Australia that much more special by topping it off with a cruise.The best off-the-beaten-path luxury vacation destinations are within reach whether you want to stay here in the US or travel to the most remote continent of Australia. From a luxury tent in the plains of Africa to the finest of hotels in Tokyo, choose from remote beaches to fine dining and shopping. Extend and enrich your 5-star stay by adding an RV rental or cruise to your next luxurious vacation.